across plasma membranes, simulating receptor-activated signaling (e.g., by vasopressin).

Based on the search results, refers specifically to a chemical product from Sigma-Aldrich : Guanosine 5′-[γ-thio]triphosphate tetralithium salt (GTP-

Solutions are very unstable; they must be prepared immediately prior to use.

Soluble in water, commonly used at high concentrations (e.g., ≥75is greater than or equal to 75 5. Regulatory and Safety Storage Class: 11 (Combustible Solids).

Because the protein cannot break down the analog, the G-protein remains locked in its active, bound state. Activation Mechanism: It binds directly to G-protein -subunits. 3. Key Research Applications