Authoritative guidelines and practice manuals for locoregional surgery include:

American Society of Breast Surgeons' performance guidelines for breast-conserving surgery. Locoregional Treatment for Early-Stage Breast Cancer - PMC

This involves removing the entire mammary gland. Depending on the case, skin-sparing or nipple-sparing techniques may be used to facilitate breast reconstruction , which can be performed immediately or as a secondary procedure. Axillary Management (Lymph Nodes)

A more extensive removal of lymph nodes (typically 7–9), recommended if malignancy is confirmed in the axilla through biopsy or if SLNB results are positive. Complementary Locoregional Therapy

Managing the lymph nodes in the armpit (axilla) is critical for staging and preventing recurrence:

Detailed 2021 thesaurus on locoregional treatments for non-metastatic infiltrating breast cancer.

Postoperative radiation is mandatory after BCS to ensure local control and is often required after mastectomy for patients with high-risk features or nodal involvement.