To run Pro Tools 10 as intended, you generally need specific Avid hardware:
Pro Tools 10 is a 32-bit application. This means it can only access a maximum of 4GB of RAM for the application itself, regardless of how much RAM is in your computer. (The Disk Cache feature mentioned above is a workaround that uses a separate system memory allocation). Avid Pro Tools HD 10
This is the "running out of CPU" error. In 32-bit systems, this often happens if you push the plugin count too high. To run Pro Tools 10 as intended, you
Accel Core and Process cards (PCIe) or the older PCI-X cards. Avid Pro Tools HD 10