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: It is strictly contraindicated in children under 12 years of age and in children under 18 following surgeries like tonsillectomies due to the risk of fatal respiratory depression.

: Crushing, chewing, or snorting the extended-release product can lead to an uncontrolled delivery of codeine, which may result in a fatal overdose. 110353

: Acts directly on the cough center in the brain to suppress the cough reflex. Key Assessment & Safety Monitoring : It is strictly contraindicated in children under

: Because opioids can cause significant constipation, bowel function should be routinely monitored. Patients are often encouraged to increase fluid and fiber intake or use stimulant laxatives if treatment exceeds 2–3 days. Contraindications and Risks Key Assessment & Safety Monitoring : Because opioids

: Antihistamine combined with an opioid agonist.

: Allergy, cold, and cough remedy; antitussive.

According to the Davis’s Drug Guide , healthcare providers must monitor several critical factors: